The Relationship between Gestational Diabetes and Subclinical Hypothyroidism in Pregnancy: A Narrative Study

Thyroid disorders and gestational diabetes are the most common endocrine disorders during pregnancy. Given the important role of thyroid hormones in glucose metabolism and homeostasis, it seems that thyroid disorders can have significant effects on glucose metabolism and insulin secretion and may contribute to gestational diabetes. This review aimed to investigate the association between gestational diabetes and subclinical hypothyroidism in pregnancy.

The results of previous studies on the relationship between hypothyroidism and gestational diabetes are inconsistent. Evidence suggests an association between thyroid autoimmune disorders and gestational diabetes.

Considering the differences in race, geographic region, genetic factors, environmental factors, diagnostic criteria for gestational diabetes, and the cut-off thresholds for thyroid function during pregnancy in different studies, it is not possible to confirm the association between gestational diabetes and hypothyroidism in pregnancy.