Case Report: A Report of Tranexamic Acid Ampoule Effect on Uterine Atony After Normal Vaginal Delivery

PPH is one of three main causes of maternal mortality in the developing countries. Atony is responsible for 75-90 % of PPH. In the lack of essential actions for reparation there will be substantial increase of maternal deaths. Recently TXA benefits in reduction of PPH is considered by many researchers. TXA is a finaquinolysis inhibitor. It’s been years TXA is commonly used in surgeries such as coronary artery bypass craft, scoliosis, orthoplasty as well as idiopathic metrorrhagia. 

A  24 years woman  G2P1L1 was admitted in Hospital for termination of pregnancy. (GA=40 w+4d) The main complaints were reduction of fetal movements and AFI=6-8cm.Misoprostol inserts for labour induction, after 6 hrs induction continues with oxytocin. By normal delivery baby  with normal Apgar score has been born weighing 3100 gr. Placenta and appendix normally delivered. But the uterine was sleazy and atonic. Hemorrhage was +1. Corrugate has been done, there was no remains. Uterotonic agents such as syntosinon, methergine, sublingual misoprostol and two hand uterine massage has been performed. But there was persistently uterine atony and active hemorrhage. Afterwards, finally Amp Tranexamic Acid has been used. Behind 10 minutes of IV injection uterine was well contracted with normal bleeding.

According to literatures and anti fibrinolytic effect of TXA we can use this medicine for resistant atonic uterus.