Associacion between blood sugar control on unstimulated saliva and Xerostomia

Xerostomia is a distressing complication of diabetes that can reduce the quality of life of the patient, which is largely due to poor blood sugar control and medications that decrease the function of the salivary glands. Conclusively, the aim of this study was to investigate the association of Blood Sugar Control on Unstimulated Saliva and Xerostomia.

In this study, 30 diabetics (Fasting Blood Sugar (FBS) ≥126mg/100ml), 30 pre-diabetics (FBS 110-126mg/100ml) and 30 healthy individuals (FBS <100mg/100ml) were selected from the patients who were referred to the Kowsar Hospital of Semnan after obtaining informed consent. The demographic information, level of FBS, HbA1C and unstimulated Saliva was evaluated and data were statistically analyzed.

According to the HbA1c results, the mean standard deviation of unstimulated saliva in controlled diabetic group was 0.08 0 ± 0.02 ml/min and 0.06 ± 0.02 ml/min in uncontrolled group, which indicated a significant difference (P=0.006). Unstimulated saliva in diabetic patients was 0.02 ± 0.07 ml/ min and ± 14.0 ± 02.0 ml in the control group (P<0.001).

Elevating FBS decreases unstimulated saliva and on the other hand increases Xerostomia. Since patients with uncontrolled diabetes have more dry mouth, blood sugar levels and its control has a significant effect on reducing unstimulated saliva and Xerostomia.