Effect of Resveratrol as a natural polyphenolic compound on liver enzymes and growth factors of Zebra fish (Danio rerio)

The present study was performed to determine the effects of resveratrol as a natural polyphenol on growth and nutrition indices of zebrafish (Danio rerio). Resveratrol was performed over a period of 60 days on 120 adult zebrafish with approximate weight of 2 ± 0.3 g and length of 3 ± 0.5 cm, which were randomly divided into 2 main groups, each of which consisted of 4 subgroups (a total of 8 Treatment) were divided as follows: The two main groups under the influence of added glucose in aquarium water (+ G) and without glucose (-G) and each of these two groups into 4 subgroups (control = CTRL) , (resveratrol = RSV ) With doses of 20, 10 and 30 micromole per liter. Fish were randomly distributed in 5 pieces into 24 tanks (3 treatment in 3 replicant) with a water volume of 3 liters. At the end of the period, weight gain, feed conversion ratio, protein efficiency ratio, specific growth rate and body growth index and enzymes of aspartate aminotransferase (AST), alanine aminotransferase (ALT), alkannin phosphatase (ALP) were evaluated. According to the results, the highest feed conversion ratio belonged to the resveratrol 20 group under the influence of glucose (G + RSV30). The highest rate of protein efficiency ratio, specific growth rate and body weight gain belonged to the glucose-free control group and no significant difference was observed between treatments. Also, the treatment of resveratrol 20 group without glucose (G-RSV20) had the lowest amount of enzyme (ALP) and no significant difference was observed with other groups and the treatment of control group without glucose (G-CTRL) had the lowest amount of enzymes (AST) and (ALT) and a significant difference was observed with other groups (p <0.05). The results of this study indicate that resveratrol did not have a positive effect on growth indices and AST and ALT enzymes but improved ALP enzyme function.