Evaluation of the Application of Polylactic Acid Bioactive Scafolds in Reconsructive Medicine

Reconsructive medicine is a growing feld for repairing damaged tissues in living organisms and is now proposed as a new treatment. For this purpose, polymeric biomaterials (scafolds) and living cells are used. The aim of this sudy was to invesigate the application of bioactive polylactic acid scafolds in the regeneration of various tissues.  Polylactic acid is a synthetic biopolymer that has been proposed in recent years as an important proposal in the production of tissue engineering scafolds. This polymer is a biocompatible, biodegradable and biosorbable material that is completely hydrolyzed in the living organisms and decomposed into water and carbon dioxide molecules. Production of bioactive polylactic acid scafolds that are able to chemically bond with hos cells after in vivo implantation is a very new method in cell therapy. This method has a great impact on the process and speed of repair of various tissues such as urethral tissue, abdominal wall tissue, periodontal ligament, heart tissue, corneal tissue, bladder tissue, vascular tissue, tendon tissue, cartilage tissue, skin tissue, nerve tissue, and bone tissue. In this article, the lates and mos prominent research of clinical scientiss in the world in 2020 and 2021, in order to produce bioactive polylactic acid scafolds for regeneration of body tissues is briefy reviewed.