Electrochemical Detection of Uric Acid by using NiO Nanoparticles

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Article Type:
Research/Original Article (دارای رتبه معتبر)
Abstract:
High and low-level concentrations of uric acid (UA) lead to several diseases and physiological disorders. A simple method or sensor is required for the detection of UA. In this work, we have prepared a NiO nanoparticles/ carbon paste electrode (NiONPs/CPE) as an electrochemical sensor and applied it for the detection of UA. Electrochemical parameters such as the effect of pH, scan rate, and concentration were studied. The obtained results represent the excellent electrocatalytic activity of NiONPs/CPE with a diffusion-controlled electrode process. The electrocatalytic process was pH-dependent with a slope of 59 mV/pH. Peak current increased linearly with the increases in UA concentrations. The detection limit was found to be 0.1 mm for the linear range from 0.19 mM to 49 mM. The NiONPs/CPE electrodes exhibited good sensitivity for the detection of UA. As a result, this work is expected to be used for the development of a sensor for the detection of UA.
Language:
English
Published:
Analytical & Bioanalytical Electrochemistry, Volume:14 Issue: 4, Apr 2022
Pages:
432 to 443
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