Mechanism of Immunity in Covid-19 Based on the Results of A Study from 254 Patients Infected with SARS-COV2

Covid 19 caused by SARS-COV2 has spread all over the world and has caused high mortality, social and economic damage so many attempts have been made for controlling and preventing the spread of the disease. One of these activities is to carry out a general vaccination program and to establish public immunity.

This article reviewed the results of a study that was performed on 188 recovered Covid-19 cases. Various immune system parameters were assessed in 254 samples of those188 patients.

It was found that immunity was heterogeneous in different individual. In most cases the patients are immune for 6 months after recovery but some with weak immunity might become re-infected. Cellular immunity plays an important role in recovery and reducing the severity of the disease whereas antibody has less effect in recovery but is important in preventing re-infection. Antibodies against S and RBD were stable up to 6 months after recovery and similarity.

Among the 6 immune parameters studied. 3 of them were stable for 6-8 months which hopefully will be sufficient for immunity and protection.