The relationship between ACTN3 gene polymorphism and athletic performance of Adolescents male

The aim of the present study was to investigate the relationship between ACTN3 gene polymorphism and adolescents male' exrcise performance. Subjects included 86 adolescents male of 8-12 year old boys from Ardabil city. ,endurance of the muscles of the fingers, endurance of the abdominal muscles, muscular endurance of the shoulder girdle, strength, cardiorespiratory fitness and speed was measured. The polymorphism of the ACTN3 gene was determined and compared using the Tetra-ARMs PCR polymerase chain reaction and direct DNA sequencing through a salivary sample. Chi-square test was used to evaluate polymorphisms. The results showed a significant difference in the frequency of polymorphism of ACTN3 gene in the subjects, which were the highest frequency in heterozygous genotype (RX), healthy or wild homozygote (RR) and homozygous metantisot (XX), respectively. The relationship between ACTN3 gene polymorphisms and students' athletic performance at three levels (weak, medium and good) showed a significant relationship only in the results of aerobic endurance test. It can be concluded that the subjects with RR genotype had better performance in strength, cardiorespiratory fitness, abdominal muscle endurance, flexibility , and the subjects with RX genotype were better. The sequence performed better in endurance of the fingers, the speed of endurance, the muscles of the shoulder girdle, the flexibility and the strength.