Validation of human urinary dipsticks for different biochemical parameters in dog

Urinalysis provides the valuable information about physiological and pathological conditions of the patients. The aim of this study was to determine accuracy of human urinary dipsticks for assessment of different biochemical parameters such as pH, specific gravity, protein, glucose, bilirubin and leukocyte in canine urine samples. For this purpose, urine samples of 60 dogs were collected and paired measurements of the urinary parameters with both different commercial dipsticks (Kimia and MN) and standard tests were analyzed. The correlation coefficient was fair between the assayed urine protein with two urine strips and standard method (r=0.68). For glucose, correlation coefficient was good between reference method and the urine strips (r=0.78). In the case of protein and glucose, both strips showed excellent sensitivity and negative predictive value (NPV). Correlation coefficient was good between reference method and the urine strips (r=0.91). Although correlation was significant between urine specific gravity assayed using refractometer and strips (r=0.38), correlation coefficient was poor. It seemed that employing human urine strips was not suitable method for evaluating specific gravity and refractometer was preferred. In conclusion, it is suggested that human urine strips can be used to determine protein, glucose and pH in urine of dog.