Super Paramagnetic Iron Oxide Nanoparticles: an overview of its synthesis, properties and application in Magnetic Resonance Imaging (MRI)

Nowadays, nanoscience and the use of nanoparticles have become very important in all fields of medicine and biology. Thus, researchers have been studying a variety of synthesis methods and to improve diagnostic and therapeutic methods, the most appropriate method have been used. The selection of the best nanoparticles and the most practical method for their synthesis is significant. The purpose of the present article was to review the types of nanoparticles, to select the most suitable nanoparticles according to their application, and finally to choose the most appropriate method for the synthesis of magnetic nanoparticles.

A review study was conducted on several selected articles based on our searches in Google Scholar, PubMed, and Scopus databases from among papers published in English between 2020-2001. Using the keywords “Nanoparticles, Magnetic Nanoparticles, Synthesis,Magnetic Resonance Imaging", the total number of articles obtained was more than 3000. First, most of the review articles were deleted and, finally, the abstracts and data of 121 English articles, which were more relevant to the keywords, were selected and reviewed.

Among different synthesis strategies, in keeping with unique research, the thermal decomposition approach is taken into consideration in medicine, particularly magnetic resonance imaging, because of its low dispersion product and manipulation over the scale and form of magnetic
nanoparticles.