Evaluation of Candida Albicans Adhesion to Two Different Types of Acrylic Resin

A common infection in complete or partial denture wearers is denture stomatitis. One of the most important factors in the adhesion of Candida albicans is the surface and chemical properties of the denture base materials. The aim of this study was to investigate the surface roughness and adhesion of Candida albicans to two different types of acrylic materials.

In this experimental study, 16 samples were prepared from each of Vertex and Ivoclar acrylic resin. The surface roughness of the samples was measured by a profilometer. The samples were then placed in a cell suspension of Candida albicans. After incubation and staining with acridine orange, the yeast cells attached to the acrylic samples were counted using a fluorescent microscope. Data were statistically analyzed by T-test.

 This article is approved by the ethics committee of Arak University of Medical Sciences with the ethics code: IR.ARAKMU.REC.1398.301.

There was no statistically significant difference in the mean of surface roughness between the two study groups (P = 0.311). However, Candida albicans colonization in ivoclar acrylic was significantly lower than vertex acrylic. (P = 0.000).

Differences in surface topography and physical and chemical properties of Vertex and Ivoclar acrylic resin affect the adhesion of Candida albicans.