Effect of Aerobic Training along with Garlic on Oxidative Stress Index in Obese Women with High Blood Pressure

A large amount of evidence shows that oxidative stress plays a central role in hypertension pathophysiology. The aim of this study was to examine effect of aerobic training along with Garlic on oxidative stress index in obese women with high blood pressure.

In this clinical trial study, 36 postmenopausal obese women with hypertension were purposefully and accessibly selected from Sari and were simple randomly divided into four groups Control (C), Aerobic Training (AT), Garlic (G) and Aerobic Training +Garlic (ATG). The training groups participated in a progressive aerobic training for eight weeks, three sessions a week (55% to 65% of the reserved heart rate and for 30 to 55 min). The groups of G and ATG were provided 1000 mg of garlic supplement for eight weeks (After breakfast and dinner). Two days before and after the protocol, blood samples were taken in fasting state. SPSS 16.0 software was used for statistical analysis. Data were analyzed using ANCOVA at p<0.05.

The results showed that the levels of malondialdehyde (MDA) (P=0.0001) decrease significantly in the experimental groups. Also, superoxide dismutase (SOD) (P=0.001), glutathione peroxidase (GPX) (P=0.000) and catalase (CAT) (P=0.001) in the experimental groups increased significantly compared to the C group. The amount of SOD, GPx and CAT in the ATG group was significantly higher than the AT and G group (p≤0/05).

It seems that AT and G has interactive effects on reducing Oxidative Stress in obese women with high blood pressure.