Evaluation of Metabolomics of Fungal and Bacterial Colonies using GC-MS

Natural sources are one of the main sources for drug discovery and identification and isolation of natural compounds with biological properties. Due to the existence of different diseases and the creation of new diseases, new drug discoveries are important. The compounds of natural origin are divided into primary and secondary metabolite categories. Most of the production compounds of various microorganisms, especially fungi and bacteria, will be very important due to their rapid growth and exogenous secondary metabolites. Moreover, the comprehensive metabolomics studies of fungal and bacterial colonies are important sources of drug discovery. Natural compounds are examined in two qualitative and quantitative methods. Qualitative and quantitative analysis of compounds is done based on microchemical studies based on precipitation or characteristic and spectrophotometry. The process of separation of the natural compounds is done using many methods, salting out and chromatography methods are among the most important applied methods. The aim of this study is the analysis of metabolomics of fungal and bacterial compounds using gas chromatography-mass spectroscopy method to discover new drugs. GC-MS device has the ability to analyze and identify compounds in extracts and other natural sources due to having a library of compounds. In this technique, the analysis compound must have a boiling point lower than about 250 oC or escape with the derivatization process to be analyzed by this metho