Effects of 4 weeks resistance training with and without blood flow restriction on GH, IGF-1, NO and Lactate in male rock climbers

Angiogenesis and increased capillary density of skeletal muscle is one of the potential physiological changes during the flow restriction exercise (BFR). Therefore, the aim of this research was to evaluate the Effects of 4 weeks resistance training with and without blood flow restriction on GH, IGF-1, NO and Lactate in male rock climbers. In this semi-experimental study, 20 elite climbers (aged 23±1.43 years; body fat percent 13.1±2.25%; 2 years athletic training history) in a randomized and double-blind design were divided in two equal rock climbing with blood flow restriction (BFR) or rock climbing without blood flow restriction (NBFR) groups Resistance training program was three sessions per week for 4 weeks and each session was 80 minutes with a training intensity of 30% of maximum strength and six movements. Blood samples were obtained in the 4 phases: before and 24 hours after rock climbing protocols in per and post-test. Vascular endothelial growth factor and Growth Hormone were analyzed. Finally, Data were analyzed independent and independent T test. The significance level was set at p<0.05. In the pretest, the increase in concentrations of IGF-1, NO, growth hormone and lactate in the BFR group was greater than NBFR (P <0.05). In addition, the increase in resting NO values was significant only in the BFR group (P <0.05) but the change in resting levels of IGF-1, GH and blood lactate was not significant in the NBFR group (P <0.05). Also, the exercise induced response of IGF-1, NO and GH increased significantly in the .