A Child with Massive Pericardial and Pleural Effusion and Chronic Granulomatous Disease

 chronic granulomatous disease (CGD) is a genetic disease characterized by recurrent life-threatening fungal and bacterial infections and granuloma formation. Pericardial effusion is rare in this disease.

 The study reports a 13-year-old boy with CGD and a history of recurrent infections such as pneumonia and abscesses. The patient presented with shortness of breath, cough, abdominal pain, and chest pain and was diagnosed with severe pericardial and pleural effusion. The patient was treated with antibiotics, antifungals, and steroids and finally underwent pericardiotomy.

 Treatment of CGD patients with recurrent infections and inflammatory lesions is challenging and requires individual decision-making for each patient.