Demographic Characteristics and Disease Manifestations in People With Pancreatic Adenocarcinoma Referred to Firoozgar Hospital: A Retrospective Study

Objective:

 Assessment of patients’ demographic characteristics and symptoms of pancreatic adenocarcinoma are of particular importance to find possible risk factors. This study aims to survey the demographic characteristics and disease manifestations in patients with pancreatic adenocarcinoma.

Methods:

 This retrospective study was conducted on 600 patients with pancreatic adenocarcinoma referred to Firoozgar Hospital in Tehran, Iran in 2020. Disease manifestations and general characteristics of patients including family and personal history of disease, and blood group of patients were extracted from their files. Then, they were analyzed using descriptive statistics.

Results :

The Mean±SD age of patients was 62.02±13.31 years; 58.7% were male and 41.3% were female. The most common site of adenocarcinoma was in the head of the pancreas (65.2%). The most common blood group was O+ (9.5%), and the main disease symptom was abdominal pain (75.3%). Among the risk factors, the most common factors were cigarette smoking, family history of other cancers, opium use, diabetes, hypertension, history of gallstones, and history of gallbladder polyps. The least common risk factors were history of extrahepatic gallstones, history of primary sclerosing cholangitis, history of viral hepatitis, methadone use, alcohol use, and history of pancreatitis. None of the patients had a history of inflammatory bowel disease or gallbladder polyps.

Conclusion:

 Cigarette smoking, family history of other cancers, opium use, history of type 2 diabetes, and history of hypertension are the most common risk factors of pancreatic adenocarcinoma.