Evaluation of the effects of 9 weeks of aerobic exercise with and without saffron supplementation on liver enzyme AST and HOMA-IR in obese female patients with type 2 diabetes

Diabetes is a metabolic disease that can be controlled through a variety of methods such as exercise, diet and medication. The aim of this study was to evaluate 9 weeks of aerobic exercise with saffron supplementation on liver enzyme AST and HOMA-IR in obese female patients with type 2 diabetes. 44 volunteer obese female type 2 diabetics in Kermanshah province with an average (age: 50 to 60 years, weight: 70 to 80 kg) in a purposeful and random manner to 4 groups of 11 people (exercise + supplement, exercise + placebo, supplement and Placebo) were divided. According to some human studies, a daily dose of 200 mg of saffron powder once a day as well as 200 mg of wheat flour was used as a placebo for 9 weeks. The exercise program consisted of 15 minutes of warm-up and 20 minutes of activity with an intensity of 50 to 55% of the maximum heart rate, which was added to the training time by 5 minutes every week and by 5% every two weeks to an intensity of up to 9 weeks of activity. Pre- and post-test blood samples for AST and HOMA-IR indices obtained with German Greener kits were evaluated based on correlated T-test, one-way analysis of variance, as well as LSD and Cohens d post hoc tests with a confidence level of 0.05. The results showed that aerobic exercise on can