Evaluation of Visfatin levels in Gingival Crevicular Fluid in Association between Coronary Heart Disease and Chronic Periodontitis

The aim of this study is to evaluate the Visfatin levels in Gingival Crevicular Fluid in Association between Coronary Heart Disease and Chronic Periodontitis.

This matched case control study was conducted on 60 CHD patients and 60 controls. These participants were divided to four groups as follow: 1) patients with both CHD and CP (n=30), 2) patients with CHD and  without CP (n=30), 3) patients with CP and without CHD (n=30), and 4) healthy subjects (n=30). The amount of visfatin in GCF samples of these participants were evaluated by  Enzyme Linked Immunosorbent Assay (ELISA).

The amount of visfatin in GCF of CHD patients with CP and CP patients were significantly higher than healthy subjects (P<0.001).

Visfatin levels in GCF of CHD patients with CP and CP patients can help to better understand the probable inflammatory process of the CHD and CP