A Review of the Use of Paraprubiotics in Aquaculture

Complications caused by the use of chemical drugs such as antibiotics in aquaculture raise the necessity of using antimicrobial compounds that are compatible with the environment. Probiotics are live bacteria that have a significant impact on host health due to their ability to control infectious diseases. Due to the possible transmission of risks from live microbial strains to the host, the use of non-living microbial counterparts has been suggested. The non-living microbial part (paraprobiotic) like its living counterpart is used as a suitable substitute orally or by injection due to its beneficial effects on the host. Therefore, the use of paraprobiotic compounds, despite their high ability in comprehensive host microbial modulation, still needs to be evaluated more carefully. In this review study, the concept of paraprobiotics, the preparation of paraprobiotics and the evaluation of health indicators of paraprobiotics in order to modulate biological reactions are described.