Simultaneous Determination of Acetaminophen in the Presence of Adrenaline at BiVO4/MCPE: A Cyclic Voltammetry Study

In the present work, the BiVO4 nanoparticles (BiVO4/NPs) were synthesized using the co-precipitation method and characterized by the X-ray diffraction (XRD), scanning electron microscope (SEM) and energy dispersive spectroscopy (EDS) techniques. The BiVO4/NPs were utilized as electrode modifiers with carbon paste electrode (BiVO4/MCPE), and the as-prepared modified electrode surface was pretreated with NaOH (BiVO4/NaOH/MCPE). The pretreated modified electrode was used for the simultaneous determination of acetaminophen (ACOP) and adrenaline (AD) by using cyclic voltammetry (CV) and differential pulse voltammetric (DPV) techniques. The influence of variation of concentration of ACOP and AD was investigated at BiVO4/NaOH/MCPE. The limit of detection (LOD) and limit of quantification (LOQ) of both ACOP and AD at BiVO4/NaOH/MCPE, respectively were determined, the LOD was found to be 3.3 µM for ACOP and 5.9 μM for AD, and LOQ was found to be 11.1 µM for ACOP and 17.8 μM for AD, respectively. Moreover, the BiVO4/NaOH/MCPE is used for the sensitive and selective determination of ACOP and AD in real samples.