The survey of bioactive compounds extraction from Spirulina platensis algae by ultrasound-assisted ethanolic maceration

Spirulina platensis found enormous applications in agriculture, food industry, pharmacy, cosmetics, medicine, mainly because of its high nutritional content and health-promoting properties. Therefore, the extraction of bioactive compounds from it remains a challenge. The objective of this work was to investigate comparison ultrasound and maceration techniques for the extraction of phenolic compounds from microalgae Spirulina platensis. Individual food-grade solvents (water (0% ethanol), ethanol (96% ethanol)) and their mixture (50% water +50% ethanol), were used for the extraction procedures. The optimal extraction condition for phenolic compounds was found at maceration when 96% ethanol was used as the solvent. Moreover, the highest yield of carotenoids and flavonoid extraction was found by sonication when 96% ethanol was used as the solvent. The use of ultrasound-assisted food-grade solvent extraction increased the extraction of the high-value added compounds and therefore resulted in higher antioxidant activities.