The effect of vitamin D3 intake and aerobic exercise on lipid profile, TSH and depression in obese women

The prevalence of obesity and metabolic syndrome is increasing worldwide. According to research, there is a significant relationship between obesity and depression. Because depressive disorders, hypothyroidism, obesity, and lipid profile disorders are all caused by poor physical activity and poor eating habits, the aim of this study was to evaluate the effect of eight weeks of vitamin D3 and aerobic exercise on lipid profile, TSH and Depression in obese women. The subjects of the study included 384 obese women (BMI≥30) were selected by simple random sampling method and were divided into four groups of aerobic activity, D3 supplementation group, D3 supplemental aerobic activity group and control group. Serum levels of TSH, LDL, HDL, TG and TC were measured by ELISA. Beck Depression Inventory was used to assess depression before and after the interventions and SPSS program was used to analyze the data. The results showed that 8 weeks of aerobic exercise and vitamin D3 consumption had a significant effect on serum LDL, HDL, TC, TG and TSH levels and depression. There was a significant difference between LDL, HDL, TC, TG and TSH in the supplement and exercise groups (p≤0.05 In general, it can be concluded that eight weeks of moderate-intensity aerobic exercise combined with vitamin D3 improves lipid profile, TSH changes and depression in obese women.