Investigation of Pregnancy Outcomes in Mothers Infected with COVID-19: A case series from a Teaching Hospital Affiliated with Mashhad University of Medical Sciences, 2020-2021

The present study was implemented with the aim of investigating the outcomes of pregnancy in cases affected by COVID-19.

The study is a case series of a record review type, which examines the characteristics of 27 pregnant women with COVID-19 referred to the Qaem Hospital in Mashhad in 2020. The case series of all pregnant women with a positive PCR or features of COVID-19 on lung CT scans. Maternal consequences were medical records, signs, disease progress, laboratory and imaging findings, and fetal-neonatal outcomes. All data were analyzed using SPSS version 24.0 software.

The mean age of the pregnant women with COVID-19 was 31.07 ± 5.86 years. Most cases (63.0%) were in the third trimester of pregnancy and only 14.8% were in the second trimester. Cough and Fever were the most common complaints. Maternal mortality was reported in 4.7% of the cases and Neonatal death was 14.8%. Among maternal messages, preeclampsia (18.5%) was the most common. Among the newborns’ consequences, the hospitalization of newborns in the neonatal intensive care unit (44.4%) was the highest.

COVID-19 infection in pregnant women can lead to severe maternal complications, including an increased risk of maternal death and preterm delivery, as well as fetal and neonatal consequences such as fetal distress, neonatal asphyxia, admission to the neonatal intensive care unit, and neonatal death. However, to reduce the risk of infection and the associated severe side effects, COVID-19 vaccination is recommended for pregnant women.