Evaluation of the effects of bisphenol A (2 and 2 bis(4-hydroxyphenylpropane)) on antioxidant defense indices of rainbow trout (Onchorhynchus mykiss)

Bisphenol A (BPA) is a chemical used in the manufacture and hardening of plastic products. Iran is one of the top 10 countries in the world in terms of consumption of plastic products, and as a result, the release of plastic waste turns into the release of substances such as BPA in water resources and in aquaculture systems. One of the ways to evaluate the presence of chemical factors in the environment of fish is to measure antioxidant defense indicators in fish tissues. This study investigated the antioxidant defense responses of rainbow trout exposed to BPA. The liver tissue of 110 pieces of rainbow trout (55 ± 0.4 grams) were sampled after 14 days of experimental fish exposure to zero, 10 and 50 micrograms per liter of BPA for antioxidant defense indicators assay such as catalase, superoxide dismutase, malon di-aldehyde and glutathione peroxidas. All indicators were significantly increased after exposure period of 14 days to 10 and 50µg/L of BPA (P˂0.05) which confirms the possibility of benefiting from these indicators in following the trace pollution with plastic products in the water and food sources of humans and the aquatic environment.