Determine the Immunopathological Profile of the Lungs of COVID-19 Patients based on the Model of Studies conducted on the Lungs of the Iranian Chemically Veterans

Throughout history and from birth to death, human has faced three wars (with nature, with the man, and with ego) and if he/she wants to have a good life, it is inevitable to resist and defend against these attacks. One of the most obvious human-to-human wars in recent years is the aggression of the ruling regime in Iraq against the Islamic Republic of Iran on September 22, 1980. Although to some extent in this eight-year war, specialists and university professors orally passed on health experiences (health, treatment, and health management) to the next generation, they were not written as they should have been. What can be written when it can convey the message of oppression and self-sacrifice of that time to today's young generation that can also play a role in solving current problems. One of the applications of these experiences is comparing immunopathological studies of chemically injured lungs with lungs of COVID-19 patients. Coronaviruses commonly cause pulmonary and internal infections in humans and animals, and in China in 2002 and 2003, they were considered almost benign viruses before the discovery of the potential for the acute respiratory syndrome (SARS-CoV). A decade later, the Middle East Respiratory Syndrome Virus (MERS-CoV), which had clinical manifestations similar to SARS, was identified in patients with pneumonia. SARS-CoV-2, SARS and MERS are of animal origin and have evolved into a form that can cause infection and fatal disease in humans. Genome sequencing showed 79% similarity of SARS-CoV-2 to SARS and 50% to MERS. Also, amino acid sequencing of some proteins indicates 68% similarity of SARS-CoV-2 proteins to SARS. Clinical symptoms of COVID-19 similar to SARS and MERS include fever, fatigue, and pulmonary symptoms such as cough, and shortness of breath. Radiological findings showed involvement of both lungs in most patients (81%) with COVID-19 with manifestations such as ground-glass opacity, crazy-paving pattern, and consolidation lesions. Laboratory findings also indicate lymphopenia and increased levels of acute-phase protein (C-reactive protein). In this disease, a portion of patients suffer from acute respiratory distress and require hospitalization in special conditions (ICU), and unfortunately, some have found a critical condition that can lead to death.