Investigating the Antibacterial Effect of Zinc Oxide / Banana Peel Bionanoparticles on Multidrug-resistant Uropathogenic Bacteria Isolated from Children Under Two Years of Age
Urinary tract infections have significant complications and high costs and can lead to death. Appropriate treatment has been challenged due to high drug resistance. The aim of the present study was the biosynthesis of zinc oxide nanoparticles/banana peel on multi-drug resistant uropathogenic bacteria in children under two years of age.
In this study, bionanoparticles of zinc oxide/banana peel were synthesized and the structural, optical, morphological, and particle size characteristics were investigated using X-ray diffraction, ultraviolet absorption spectrum, and scanning electron microscopy. Biochemical tests and Colony-PCR technique were used to identify bacteria. The antibacterial properties of the synthesized nanoparticles were evaluated by the Agar dilution method on isolated bacteria.
According to the XRD, SEM, and UV-Vis results, the synthesized zinc oxide had a hexagonal structure with a size of 100 nm and absorption at a wavelength of 258 nm. Bacterial strains of Escherichia coli, Proteus mirabilis and Klebsiella pneumoniae multidrug-resistant Uropathogenic bacteria were identified using morphological, biochemical, and molecular characteristics. The results of antibacterial tests showed that bionanoparticles of zinc oxide/banana peel at a concentration of 0.6 g/L were effective against all bacteria.
The findings of this research showed that zinc oxide/banana peel bio-nanoparticles had an effective antibacterial effect against multi-drug resistant UTI bacteria in children under two years of age.
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