Evaluation of the antibacterial and antioxidant properties of green nanoparticles synthesized from the extract of Datura plant
In the range of nanostructured materials, metal nanoparticles are of great importance, especially in medical sciences, and their green synthesis is safer compared with chemical synthesis. The current research aims to investigate the possibility of green synthesis of silver nanoparticles using Datura extract and to evaluate its antibacterial and antioxidant properties.
In this research, after nanoparticle synthesis using UV-Vis spectrophotometer, the spectrum of treatments in acidic and alkaline pHs, the concentration of extract and nanoparticle, temperature and time were evaluated, and then the size and morphological characteristics, active groups and ion-reducing groups were evaluated. Finally, antimicrobial properties (halo diameter by disk method, MIC and MBC) and antioxidant properties were determined by DPPH and ABTS method.
The findings showed that the optimal pH is equal to 6.5, the optimal concentration of silver nanoparticles and extract is 3 ml and 3 mM, respectively, and the optimal time is 10 minutes. The structure of nanoparticles is spherical and their average size distribution is 24.10 nm. Antimicrobial effects with the help of disk diffusion method showed that the most antimicrobial effect was on E.coli bacteria and the least effect was on Streptococcus pneumoniae bacteria, and finally, the antioxidant properties were optimal with increasing concentration of silver nanoparticles compared with the standard sample.
The silver nanoparticle obtained from Datura extract can be a suitable substitute for synthetic antioxidants and antibiotics in various food, pharmaceutical and medical products.
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