Effectiveness of an Integrative Educational Package Based on Motivational Interviewing, Acceptance and Commitment Therapy, and Compassion-Focused Therapy on Alexithymia and Quality of Life in Women with Multiple Sclerosis

 The present study aimed to design an educational package based on Motivational Interviewing, Acceptance and Commitment Therapy, and Compassion-Focused Therapy and evaluate its effectiveness on alexithymia and quality of life in patients with Multiple Sclerosis (MS) in Tehran.

 This study employed a quasi-experimental design with a control group and pre-test, post-test, and follow-up assessments. Forty women with MS, who visited the MS Association in Tehran Province from October to February 2021, were selected based on research criteria through purposive sampling and were randomly assigned to two groups (using a random number table). After random assignment, one of the groups was randomly designated as the experimental group, receiving the researcher-developed integrative treatment package, and the other as the control group (n=20). The data collection tools included a demographic information questionnaire, the Toronto Alexithymia Scale (Bagby, Taylor, & Parker, 1994), and the Multiple Sclerosis Quality of Life-54 Instrument (Ware et al., 1988). Data were collected at three stages: baseline, post-intervention, and three-month follow-up. The research hypotheses were analyzed using repeated measures ANOVA and Bonferroni post hoc tests.

 The results of this study indicated that the educational package based on Motivational Interviewing, Acceptance and Commitment Therapy, and Compassion-Focused Therapy significantly improved alexithymia (F=24.31, P<0.001) and quality of life (F=22.67, P<0.001) in women with MS.

 It can be concluded that the educational package based on Motivational Interviewing, Acceptance and Commitment Therapy, and Compassion-Focused Therapy is effective in improving alexithymia and quality of life in women with MS.