Comparison of antifungal and antibacterial effects of Persica Matrica and Iralwex with Chlorhexidine mouthwashes (An in vitro study)

Global approach to the herbal medicine has resulted in research activities to be focused on the findings of scientific documents in this field. The aim of this study was to investigate the antibacterial and antifungal effects of three herbal mouth washes (Persica, Matrica, Iralwex) and two chlorohexidine - based commercially available mouth washes. Methods & Materials: The microbial ssp tests were performed using catalase, optochin, bacitracin and gram staining. Cellular suspensions with a concentration of 0.5 Mc Farland were prepared. The inhibition zone was assessed by Disk diffusion method. The minimum inhibitory concentration (MIC) of each mouth wash for each micro-organism was determined by using Dilution Tube Technique. The results were analyzed and compared using ANOVA at a significance level of (p<0.05). The results showed that the effect of the herbal mouth washes on the micro- organism was less than the two other chlorhexidine-based mouth washes (P<0.01). The antibacterial effects of the herbal Matrica compared to the two other herbal mouth washes were significant. The comparison between the herbal and chlorehexidine-based mouth washes showed that the antibacterial effects of the herbal Matrica compared to the two other herbal mouth washes was significant. More research is needed for improvement of the herbal mouth washes.