Effect of short term glutamine supplenmentation on cortisol and salivary flow rate in active boys after on bout of exhaustive exersice

The purpose of this study was to examine the effect of short term glutamine supplementation on cortisol and salivary flow rate in active boys after one bout of exhaustive exertion. Twenty four active boys  (age 18.77 ± 1.2 yr, body mass 57.42 ± 4.5 kg, peak whole body oxygen uptake 42.96 ± 2.31 ml.kg-1.min-1) were randomly assigned in a double-blind fashion to either glutamine treatment group or placebo group. Subjects performed the Bruce maximal test to exhaustion for two separate days and with a four-day interval. L-Glutamine supplement mixed with sugar free lemonade (0.1 g/kg) or placebo (only sugar free lemonade) was given during interval between tests. Unstimulated salivary samples were collected at 7 min (for evaluating of salivary cortisol concentration) and salivary flow rate at 20 min after performing the Bruce maximal test. The statistical analysis  (P<0/05) using dependent and independent t-test showed a significant effect of short term L-glutamine supplementation on levels of Salivary cortisol concentration and also salivary flow rate but no effect on between-groups levels of these factors. This study does not support that decrease in plasma glutamine after a bout of exhaustive exertion is related to immune impairment.