Effectiveness of Neoadjuant Treatments on Mortalities And Short-term Complications in Esophageal Cancer Patients Undergoing Transhiatal Surgery at Emam Reza (Pbuh) Hospital of Mashhad (Iran)

Although surgery is the corner stone of treatment for esophageal cancer, there have been widespread efforts to find new methods of treatment. Therefore, neoadjuant CRT certainly increases the rate of resectability and 3 years survival. In our research, we reviewed effects of neoadjuant RCT on short-term complications and hospital mortalities. 114 cases of esophageal cancer during a two-year period underwent operation by trans-hiatal method. Based on the size and pathologic reports, neoajuant CRT was applied for a subgroup. Most the tumors were in middle one/third and male to female ratio was 4 to 1.There were 13 complications and 6/3% mortalities. No significant differences were observed between the two groups.Discussion & Conclussion: Neoadjuant treatment does not increase mortality or complication of surgically operated esophageal cancers. More well-controlled studies by different centers with more cases are recommended for more reliable achiements to be reached.