Determination of ultrasonographic hepatobiliary abnormalities in Thalassemia mojor patients referring to Kerman university hospital No.1

One of the complications of Beta-thalasemia major is hepatobiliary disorders for example cholelithiasis (Gallstone). In this study frequency of hepatobiliary ultra sound abnormal findings in 200 patients in Kerman was investigated. Among 200 patients, 11 (5.5%) had gallstone. The average age of patients without gallstone was 10.07±4.9 years and that of patients with gallstone was 16.1±5 years. Therefore significant difference in this regard is observed (P<0.05). Five patients (2.5%) had thickened wall in gall bladder, and their mean age was 12±2.5 years and that of patients with normal wall thickness was 10.3±5.1 years with no significant difference between two groups. Sixty three patients (31.5%) had history of splenectomy and 137 patients (68.5%) had not this history. Among 11 patients with gallstone, 9 patients had history of splenectomy and 2 patients had not this history with significant difference between the two groups (P<0.05). No significant difference was observed in the average serum ferritin in patients with gallstone (3786.7±941.4) and in the patients without gallstone (3147.03±1239.7).