Pre-induction Sedation with Intranasal Midazolam in Children

Surgical procedures are one of the most stressful experiences in life, especially in children, and different methods are used preoperatively to decreasing this stress. Intranasal midazolam is an effective method for preparing the children before operation and prevents separation irritability.Subjects and Sixty patients aged 2-6 years that have elective surgery for the first time were chosen randomly. Subjects were randomly allocated into two groups. For the patients in group 1, intranasal midazolam (0.2 mg/kg) and for the patients in group 2, the equal volume of normal saline 0.04ml/kg was administered intranasally. Patients’ cries, irritability, hand moving during IV canulla insertion, consciousness before anesthesia and cooperation during face mask ventilation were evaluated. In group 1, 93.3% of children did not cry or cried mildly when separated from parents, 90% of children in group 2 cried moderately or severely (P