Report of one case of probable infertility due to multiple sclerosis

The issue of infertility in patient with multiple sclerosis (MS) has not been fully studied. However, it is only recently that the intricate interactions between the disease and reproductive function in women have begun to be explored. It is clear that there is important neuro-immuno-endocrine interaction at a cellular and molecular level. Dysfunctions within the hypothalamic- pituitary- gonadal axis occur frequently among women with MS and induce menstrual disturbance and subsequent infertility. Moreover, literature show that some medical treatment used in MS may exert determinable effects on germ cell which lead to infertility. These findings approved the hypothesis of probable fertility disorders during MS which lead to infertility. The aim of this case report is to introduce a women with MS and primary infertility which not only our treatment method had not decrease her fertility (corticosteroid therapy and other follow up) but also resulted in effectiveness of proposed infertility treatment and bearing child.