Comparison of effect of anti-coccidial drugs, salinomycin and maduramicin, on frequency of excreted oocytes and performance in experimental coccidiosis in broiler chicken

To compare the effect of coccidiostate drugs (salinomycin and maduramicin) on the oocyst sheding and performance of coccidi-infected broiler chicken، 180 Ross 308 Broiler chicken were randomly assigned to four treatments. Each treatment contains 3 replacements of 15 chickens. Treatment 1 and 2 fed diets supplemented with maduramicin and salinomycin until three days before experiment period، respectively. Treatment 3 and 4 were designated as positive and negative control receives no coccidiostates. Chicken in treatment 1، 2 and 3 were inoculated with a 0. 5 ml suspension containing four prevalent eimeria species in Iran (E. tenella، E. necatrix، E. acervulina and E. maxima) on 26 days of age. Frequency of excreted oocyst of feces sample from 7-16 day post-challenged was carried out. Body weight (BW)، body weight gain، feed conversion ratio (FCR) and mortality rate were determined and registered in special tables weakly. The result revealed that coccidiostate dugs decreased oocysts per gram of feces (OPG) significantly in 7-16 days post inoculation (majorly maduramicin) (p<0. 05). At the end of study effect of maduramicin on increase of body weight and feed consumption comparing to salinomycin was considerable (P<0. 05). Effect of two drugs on decrease of mortality were similar (p>0. 05). The lowest FCR was belonged to negative control followed by chickens treated with maduramicin. According to the results of this experimental trail، maduramicin could decrease the OPG significantly and improve production performance in coccidio-infected broiler chickens.