The study of chromosomal abnormalities and hetromorphism among 140 couples with recurrent abortions compared with control subjects

Translocation incidence of chromosomal balanced chromosomal abnormalities in couples with repeated abortions is from 0-31% different studies indicate that recurrent spontaneous abortions to prove Translocation balanced are helpful. In this study, 75 couples had 3 abortions and 65 couples had two abortions. These patients were referred by specialist of women investigated cytogenetically to the lab Beheshti Hospital of Hamadan. and the karyotype 40 healthy individuals without history of abortion Embryos investigated as control group and study made. this study is prospective.in this study used GTG bonding technique (stained with gymsa and trypsin). Frequency of chromosomal abnormalities and Hetromorphism between couples with three or more abortions were reported, respectively 5.3% and 9.3%. as the frequency of chromosomal abnormalities among couples with two abortions were determined for chromosomal abnormalety 3.07% and 6.15% Hetromorphism Chromosomal. Controls the frequency of chromosomal Hetromorphism of 7.5% was driven and no chromosomal abnormalities were observed in control subjects. This results show that chromosomal abnormality is one of the reasons is recurrent spontaneous abortions that more abortion increases the probability of this anomaly.also chromosomal Hetromorphism of the general population of individuals without history abortion embryos indicate that Hetromorphism Chromosomal can not be the reason of these spontaneous abortions.