Comparison the Effect of Sofentanil and Lidocaine versus Lidocaine alone in Hemodynamic Changes and Spinal Anesthesia Duration After Surgery

Spinal anesthesia is a route for anesthesia. In this route some drugs like Lidocaine, Procaine, Ropivacaine used. For decreasing the side effects and increasing the quality also duration of anesthesia added to the others drugs like Morphine, Sufentanil, Fentanyl and Epinephrine. This study was compared the effect of sufentanil and lidocaine to anesthesia in surgery. We selected randomly 90 patients who referred to Amir-Al-Momenin Hospital, Semnan, Iran from 21 June to 20 August 2008. The patients divided into two groups (S and L). The S group received Lidocaine and Sufentanil and L group received Lidocaine alone. We recorded the initiation of spinal anesthesia and its duration. Also the changes in the heart rate, systolic and diastolic blood pressure (at zero, 5, 10 and 20 minute after injection) were recorded. There were significant differences in both studied groups about some variables including; duration of spinal anesthesia (37/7 + 11/86)(P< 0.001), initiation of anesthesia effect (82/7+55/64) (P<0.001), systolic blood pressure (P=0.014) and diastolic blood pressure (P=0.008). But the other variables such as age, sex and heart rate have not any difference in two studied groups (P>0.05). This study shows that adding of Sufentanil to Lidocaine result the increase of spinal anesthesia quality and decrease the homodynamic changes.