Short term effect of 1% topical phenytoin suspension on the pain and wound dimensions of donor site after free gingival grafts

Ulcer and pain have been the most complications arised after periodontal surgery. The purpose of this study was to evaluate the healing and analgesic effect of Phenytoin in donor site of free gingival grafts. This study is a randomized clinical trial with 10 patients received free gingival graft and divided in 2 groups. The wound size measured with digimatic caliper. Donor sites rubbed in case group with Phenytoin and with placebo in control group. The wound size measured in 14th and 28th days and evaluated in comparision with baseline. Also, the pain level measured via VAS. Statistical analysis was performed using T pair test and wilcoxaon signed ranks. Statistical analysis showed that case group had better healing due to standard diviation in both appointments (α=0.1, p=0.078, and α=0.05, p=0.049, respectively). Pain Score was lower in patients treated with phenytoin (p=0.18) Phenytoin is effective in healing of donor site and reduce pain.