Journal of Kermanshah University of Medical Sciences
Volume:16 Issue: 1, 2012

Imaging studies performed in research centers suggest a high prevalence of brain structural abnormalities in patients with epilepsy. However, the results of research studies may not be directly applicable to general clinic, because they may perform on patients with high probability of cerebral abnormalities. On the other hand, more advanced modalities are likely to be used in research studies for the detection of such abnormalities. The aim of this study was to evaluate the brain CT scan findings in epileptic patients in neurological clinics.

A cross sectional study was designed and medical records of 931 patients with the diagnosis of epilepsy was assessed. Data such as: age, sex, type of epilepsy and brain CT scan findings collected from 1996 to 2007.

The mean age of the patients was 24 years. 473 patients had generalized tonic colonic seizures and 325 patients had motor focal epilepsy. Among the 905 patients with brain CT scans, 125 scans reported as an abnormal (15.8%). Abnormalities were vascular (6.4%), space occupying lesions (2.5%), malformation of cortical development (2.5%) and nonspecific lesions (2.4%). The most prevalent abnormalities were among the focal motor epileptic patients.

Although the rate of structural abnormalities in patients with focal motor epilepsy was higher but it is lower than other reports. This might represent technical errors in performing CT scans or differences in etiologies of focal motor epilepsy in various populations. More attention is recommended for performing CT scan in the patients with epilepsy.

Oral white and red lesions are usually assumed as premalignant lesions. Epidemiological characteristics of these lesions seem to be important. The aim of this study was to determine the prevalence of the oral red and white lesions in patients referred to oral and maxillofacial pathology department in Isfahan School of Dentistry during last two decades.

In this descriptive study, clinical profiles of oral pathology department from 1988 to 2008 were reviewed. Gender, age, location and type of lesions and referring time were recorded. Data was analyzed using Chi-square with SPSS 11.5 statistical software.

6509 patients referred to oral pathology department, which 1047 (16.1%) cases recorded as red and white lesions. The most prevalence red and white lesions were Peripheral Giant Cell Granuloma (PGCG) and Lichen Planus respectively. The mean age of red lesions was 33.9 ± 17.9 year with a prevalence rate of 57.8% in women. The mean age of white lesions was 44.92 ± 13.09 with the most prevalence rate of 67% in women. The most prevalent red (18.5%) and white (31.8%) lesions were related to age ranges of 31-40 and 41-50 years old. Red lesion mainly located in Gingival (79%) and white lesion in buccal mucosa (57.4%).

Prevalence of white and red lesions is increasing in the recent years. More studies are required to investigate the probability of white and red lesions malignancy.