فهرست مطالب zinat mohammadpour

Land subsidence is one of the most important geomorphic hazards that has a slow motion but destructive effects in the long run. For the spatial analysis of the amount of displacement, the data on changes of the ground surface from Sentinel A1 for a period of 3 years (2017-2020) through the radar interferometric method and SNAP software were used. Field observations were also made to evaluate the research results. The results showed that the rate of land subsidence has increased from 2017 to 2020, from 2.6 cm in 2017 to 7.8 cm in 2020. Moreover, the groundwater hydrograph in the central plain of Ghaen has significantly decreased, so that the rate of water level drop in the plain level has been about 1.30 meters during 5 years (from 2014 to March 2020), i.e, about 26 cm per year. In addition, the analysis of spatial autocorrelation and Moran index (0.984) confirmed the clustering of subsidence event under the influence of water level changes in the study area. The correlation results also showed that there was a small correlation between the factor “changes in water level” and “land subsidence rate” (p = -0.138), which is an indirect relationship, i.e., the higher the groundwater abstraction (or the lower the water level), the higher the amount of subsidence. But due to the level of significance (sig = 0.585) this relationship is not significant.

Urbanization is one of the consequences of the industrial revolution, which changed the development process and led to the expansion of migration to the city. One of the main results of the expansion of urbanization in recent decades is land use change in cities and their uneven growth, which has made managing urban growth one of the most important challenges of the 21st century. The present study evaluated the changes in the lands of Torbat-e Jam city during the years 2000 to 2019 and then predicts these changes until 1420 AH. The research method is descriptive-analytical. Landsat images, sensors, ETMs of 2000 and 2010 and OLI sensors of 2019 have been used to collect data in this study. After classifying the images, in order to find out the changes in the land use of Torbat-e Jam city and to predict the changes until 1420, the Markov and CA chain model has been used. The results obtained in the period of 2000, 2010 and 2019 show that the area of ​​all land uses in the study area except barren land use has been increasing. Also, the forecast of the four floors of land cover, including urban lands, agriculture, barren and green space and gardens in the city of Tor bat-e Jam on the horizon of 1404, shows that the land use of the city will increase at the horizon of 1420, so that this land use will change by 192.13%. Agricultural land use will have a decreasing trend with 71.05% and green space and gardens with 53.32% and barren land use area will have an increasing trend change with 100.87%. Finally, with the Vision Development Index, the type of urban growth was determined. Also, according to this index, the growth type of Tor bat-e Jam city is of the edge type.

Multiple sclerosis (MS) is an inflammatory disease of the central nervous system (CNS) with the most common complaint of fatigue. A high number of patients with MS are interested in taking dietary supplements as a complementary therapy. We propose a specially formulated supplement for patients with MS and aim to evaluate its effects on fatigue.

This study was a triple-blind, randomized, placebo-controlled trial using a stratified randomization method according to sex. 46 eligible patients participated in the study, 23 in the placebo group and 23 in the intervention group. The intervention group received two capsules of multivitamin-mineral (MVM) daily for 3 months.  Measurements of fatigue and cytokines were performed in all patients at the baseline and after the 3-month intervention

Finally, information of 41 participants was used for data analysis. However, fatigue was decreased after supplementation than before, in the intervention group (P = 0.005). There was no significant difference (P = 0.090) between the change of fatigue score in the MVM group (-3.00 ± 4.42) and the control group (-0.40 ± 5.14). Among cytokines, Interleukin 4 (IL-4) significantly increased in the intervention group compared to the placebo (P = 0.030).

Our study showed that the present MVM probably could improve the inflammatory state and fatigue in patients with MS.

The current study aimed to update prior systematic review and meta-analyses (SRMA) in order to determine the effects of supervised exercise-based cardiac rehabilitation (EBCR) and introduce a suitable exercise protocol for management of lipid profile abnormalities in patients with cardiovascular disease (CVD).

PubMed, Scopus, and Web of Science databases were searched from 1980 to December 2018. All published, randomized controlled trials (RCTs) reporting the efficacy of supervised EBCR in patients with CVD and measuring at least 1 component of lipid profile were included. The quality of articles was assessed based on the Physiotherapy Evidence Database (PEDro) scale. Random effect model was used to calculate the effect size of post-intervention data.

Initially 774 RCTs were reviewed, 14 of them were included in the study. In comparison with the control group, supervised EBCR was associated with higher serum levels of high-density lipoprotein (HDL) [weight mean difference (WMD): 1.297; 95% confidence interval (CI): -1.620, 4.214] and lower serum level of low-density lipoprotein (LDL) (WMD: -7.797; 95%CI: -14.005, -1.588), total cholesterol (TC) (WMD: -11.029; 95%CI: -20.716, -1.342), and triglyceride (TG) (WMD: -14.602; 95%CI: -28.992, -0.212).

It seems that EBCR is correlated with an insignificant increase in HDL serum level and a significant decrease in LDL, TC, and TG serum levels. Considering subgroup analysis results, it is suggested that long duration, moderate exercise volume (EV), and combination of aerobic exercise (AE) and resistance exercise (RE) be used to improve HDL and TG serum levels. Short duration, high EV, and AE+RE seem to significantly reduce LDL serum level. Moreover, moderate EV is associated with a significant reduction in TC level.

At present, no documented anesthetic technique exists for use in liver transplant surgery. Presence of some controversies in anesthesia plan led us to compare effects of inhaled and intravenous anesthetics in liver transplant surgery.

All those brain dead patients who met the criteria of organ donation were included in the study. The donor's liver is matched with the recipient according to our liver transplant protocols and assigned consecutively to the recipients. In this study 78 patients who met the inclusion criteria, were divided into two groups.All patients in group 1 were anesthetized with inhalation of sevoflurane and patients in group 2 were anesthetized with the IV injection of propofol. Percent of sevoflurane in inhaled gases and IV infusion dose of propofol was determined by a BIS guide to keep BIS between 40 and 45. Patients were monitored by NIBP, ECG, CO – Oximetry and BIS before and during induction of anesthesia. An arterial line from radial artery and Swan–Ganz–Catheter from right internal jugular vein were inserted for all patients.

Mean of PCO2, PO2 and HCO3 were different between 2 groups (p=<0.05) and were higher in propofol group. Also, mean of Na and K were different in both groups and were higher in sevoflurane group, and no other significant differences found.

The results showed that the effect of propofol and sevoflurane on hemodynamics, coagulation status during liver transplant anesthesia, and hepatic and renal function of the patients after liver transplant is the same.

Preeclampsia is considered as a serious life-threatening condition that could affect both maternal and fetal outcome. Many studies have examined the association of nutritional factors with the incidence of preeclampsia. However, little is known about the possible role of vitamin D in the development of preeclampsia among the Iranian population.

The aim of the present study was to evaluate the association between vitamin D status and preeclampsia.

A total of 120 pregnant women who were referred to Kamali and Alborz General Hospital located in the Karaj City were enrolled in this study and categorized into preeclamptic and control groups (n = 60/each). The clinical details of patients such as demographic characteristics and laboratory findings were obtained from the patients. The serum levels of vitamin D, calcium, phosphorus, and parathormone were also measured. Multivariate logistic regression analysis was used to assess for independent predictors of preeclampsia.

The mean age among pregnant women with preeclampsia and control group were 31.48 ± 5.25 and 29.01 ± 5.28, respectively. The mean body mass index among the preeclamptic group was 27.92 ± 4.98, which was significantly higher compared to the control group (p < 0.001). The serum vitamin D levels were significantly lower in women with preeclampsia compared to the control subjects (p = 0.007). Moreover, no correlation between vitamin D deficiency and predisposing factors of preeclampsia was observed after adjusting for confounding factors.

Our study revealed that serum vitamin D level is significantly lower in among the pregnant women diagnosed with preeclampsia compared to the healthy subjects. However, no correlation was observed between the vitamin D status and the risk of preeclampsia development.

Procalcitonin (PCT) has been shown as a reliable diagnostic biomarker for identifying sepsis and bacterial infection. The present study examined the sensitivity and specificity of PCT evaluation in the diagnosis of infectious diseases after liver transplantation. The present prospective cohort study was conducted on postoperative liver transplant (LT) patients in the liver transplant ward of Imam Khomeini Hospital Complex affiliated to Tehran University of Medical Sciences between January 2014 and March 2015. Serum PCT levels were evaluated before transplantation and one, two, and six or seven days post-operation by semi-quantitative kits with a 30 seconds response. A total number of 28 LT patients were enrolled in this study. The mean patients’ ages were 48.6 ± 10.9 (range 26 - 66) years old. Serum PCT levels in all patients were < 0.5 ng/mL prior to the operation. At first and second days post-operation, PCT levels were more than 2 ng/mL in all patients and decreased to 0.5 ng/mL after 6 or 7 days in 23 patients. Serum PCT level of higher than 5 ng/mL on the first and second days post-surgery with a sensitivity of 77.8% and specificity of 79% had the most accuracy for the infection diagnosis. The PCT level more than 5 ng/mL in the sixth and seventh days had a 100% positive predictive value in the infection prediction. Serial evaluations of serum PCT after liver transplantation had good sensitivity and specificity to predict postoperative infection. Increased serum PCT level within the first days after transplantation and/or failure to decrease after one week, predicts infectious complications and undesirable outcome.

Resveratrol (RSV) provides several important biological functions in wide variety of cells. In this study, we investigated the molecular mechanisms underlying anti-inflammatory effect of RSV on HepG2 cells by assessing the gene expression of RelA and c-Jun- subunits of NF-κB and AP-1 transcription factors.

HepG2 cells were settled in a serum- free medium with high concentrations of glucose (30 mM) and insulin (1 µM) overnight and were then incubated with RSV (5, 10, and 20 µM) for 24 and 48 hours. Real time quantitative polymerase chain reaction (qRT-PCR) was used to determine RelA and c-Jun expression.

RSV diminished hyperglycemia/hyperinsulinemia stimulated expression of c-Jun dose- dependently after 24 and 48 hours (p The findings of the present study demonstrated that RSV may be considered as a preventative and therapeutic agent for antagonizing inflammation in Hepatocellular carcinoma (HCC).