جستجوی مقالات مرتبط با کلیدواژه « Chromium » در نشریات گروه « پزشکی »

The desire for beauty and frequent use of cosmetics can expose humans to heavy metals, which can cause immune system disorders over time. We selected 5 common lipstick brands to determine the concentrations of cadmium (Cd), lead (Pb), and chromium (Cr). We prepared each sample by acid digestion, and then the concentration of the metals was measured using an atomic absorption spectrometer. The results showed that Pb, Cd, and Cr were present in all lipstick samples. However, their concentrations were lower than the Food and Drug Administration (FDA) standards. The maximum concentrations of Pb and Cd were 2.31 mg/kg (brand A) and 0.037 mg/kg (brand D), respectively. Health risk assessment of the examined metals showed that only Cr can pose non-carcinogenic (14.98) and carcinogenic (44.96E-04) risks to consumers. Despite the low concentration of heavy metals in our study, chronic use of lipstick can pose carcinogenic and non-carcinogenic risks due to the presence of Cr.

Inappropriate management of textile wastewater results in environmental pollution. To counter this, biofilters or biofilm systems serve as alternatives. Biofilters work like a filter, with a media stack that aids in the filtration process. In this study, pozzolan and sawdust were used as media. The present study aimed to identify the difference in average color content, chemical oxygen demand (COD), and chromium of textile wastewater after passing through a single biofilter versus a combination biofilter.

This study employs a post-test with a control design experimental research design. The research population is the total textile wastewater produced by the X industry located in Cimahi city, Indonesia. The grab sampling technique was employed to collect 30 L of textile wastewater for each treatment using both the single biofilter (composed solely of sawdust) and the combination biofilter (mixture of sawdust and pozzolan).

There are significant differences in color, COD, and chromium content averages between single and combined biofilter treatments, supported by P values of 0.012, 0.004, and 0.010. The single biofilter exhibited higher percentage reductions in color and chromium (14.25% and 90.83%, respectively) compared to the combination biofilter. In contrast, the combination biofilter achieved a remarkable COD reduction of up to 79.45%compared to the single biofilter.

The results of the present study showed that the single biofilter had a higher capacity to remove color and chromium compared to the combination biofilter. Meanwhile, the combination biofilter was found to be more effective in removing COD compared to the single biofilter.

Recently the carcinogenic and toxic effects of some heavy metals such as chromium (Cr), and lead (Pb) through the mechanism of oxidative stress have been reported. Due to the various consequences of chemotherapeutic treatments on body hemostasis, the present study aimed to evaluate the effect of Adriamycin 60 mg/m2 and Cytoxan 600 mg/m2 (AC) chemotherapy on the serum levels of Cr, Pb, and the percent α-diphenyl-β-picrylhydrazyl (DPPH) inhibition.

This study was performed on 50 patients with breast cancer at two separate sampling times, the first at the initiation of chemotherapy and the last at the end of three courses of the AC chemotherapy treatment. Serum levels of Cr and Pb were measured using atomic absorption spectrophotometry. The percent DPPH inhibition (% I) and also the effect of age and stage of the disease on the mentioned variables were evaluated. Statistical comparison of the obtained results before and after chemotherapy was performed using paired sample t-test. Intra-group evaluation of age and disease stages was done using an independent sample t-test.

A significant decrease was observed in the percent DPPH inhibition after 3 courses of chemotherapy (p<0.001). Cr and also Pb were significantly higher in patients with breast cancer after AC chemotherapy (p<0.001).

According to the results, AC chemotherapy in patients with breast cancer is associated with higher levels of Cr and Pb, which can eventually lead to worsened oxidative stress status in affected patients. However, it seems that these changes do not necessarily depend on age and the stage of the disease.

Fish smoking is the oldest known traditional method of fish processing and preservation. Fish provide the protein needed for bodybuilding and repairs of tissues, and form part of a healthy balanced and nutritious diet. Heavy metal contamination on ingested food substances is an issue of a serious health concern due to their high level of toxicological effects on humans. Fish products may become contaminated during processing or as a result of the intake of heavy metals from a polluted aquatic environment. The study was aimed at assessing the level some Heavy Metal (Pd, Cr, Cd, Hg, and As) contamination of smoked fish sold at Maiduguri fish markets. Fish samples (Smoked and unsmoked) were obtained from 8 major fish markets in Borno State. The samples were oven-dried and grounded. The grounded samples were digested using concentrated nitric acid and hydrogen peroxide (2:1) v/v and analyzed for heavy metals using AAS both at the Chemistry Department, Yobe State University, Damaturu. The results obtained, reveals that Cr, As, and Hg concentrations were below the set national permissible limits as set by NAFDAC in all sampling stations in the study area while Pd concentration exceed the set permissible limit in sample station E and F (2.768 ± 0.251 and 2.602 ± 0.241 mg kg-1 respectively). Furthermore, Hazard index (HI) values of the heavy metals (Pd, Cd, Cr, As, and Hg) were all greater than 1, revealing an unacceptable level of non-carcinogenic adverse health effects. The study recommends a continuous assessment of the level of heavy metals in smoked fish from the study area.

 The aim of this in vitro study was to assess the quantity of nickel and chromium ions released from orthodontic wires when subjected to various beverage solutions and distilled water.

 Orthodontic appliances composed of five brackets, one band and 0.016-inch stainless steel and nickel titanium wires were immersed in Coke, tea, coffee and distilled water. The samples were incubated at 37℃ for 1 hour, 6 hours, 24 hours, and one week. There was a total of 120 appliances divided into 24 groups (n=5 in each group). Atomic absorption spectroscopy was used to examine the amount of released ions. Two-way and one-way ANOVA followed by Tukey test were used for statistical analysis and P<0.05 was considered significant.

 The release of nickel ions from both wires was highest in Coke and lowest in distilled water at all time points. Coffee and tea demonstrated values in-between these two limits. Similarly, chromium ion release from both wires was highest in Coke at all time-points compared to all other solutions (P<0.05). None of the other tested drinks showed significant differences in chromium ion release compared to distilled water.

 Restricting the intake of acidic drinks, particularly carbonated beverages like Coke, plays a critical role in safeguarding orthodontic wire components. Educating patients and providing dietary guidelines are essential for maximizing treatment effectiveness. Further research is required to investigate additional factors impacting ion release and devising methods to mitigate potential harm.

Obesity is a public health and various methods are used to manage this health issue. The aim of this review was to investigate the possible effects of Chromium supplementation on body composition and body weight.

Databases such as PubMed, EMBASE, The Cochrane Library, Scopus, and Web of Science were searched for human studies in English using keywords of body weight, body mass index (BMI), fat mass, adipose tissue, total body fat, obesity, overweight, ideal body weight, weight loss, weight reduction, and chromium supplementation.

Totally, 345 articles were enrolled. The effect of 400 mcg/day intervention was more pronounced when compared to 200 mcg/day. Later, in 1998, the role of physical activity was illustrated and as a result, a significant change in body composition was seen. Volpe et al. found a slight relationship between 400 mcg/day of chromium supplementation and decrease in body fat mass (mean=1.78%/max=7.54%). Liu et al. reported no significant changes in BMI, fat mass, and fat-free mass. Moreover, Yazaki et al. investigated the effect of 1000 mcg supplementation. Still, no change was seen in BMI neither in the first 12 weeks nor whole 24 weeks of the study. It might have slightly positive effects on decreasing body fat and increasing lean body mass.

The undertaken studies mostly showed better and stronger results for the effect of chromium supplementation on body weight or fat mass when physical activity was included or higher doses were consumed.

Because of its stimulating and valuable effects, tea is the most commonly used beverage in the world after water. These effects are due to caffeine and phenolic compounds in tea. Also, most of the tea in Iran is planted in Gilan Province. However, food pollution from heavy metals is one of the most important problems. 

In this research, we measured the total phenolic content, caffeine, lead, cadmium, and chromium in green and black tea cultivated in Gilan Province.

Ten samples of green and black tea were purchased from different regions of Gilan Province. Methanol and dichloromethane extracts were prepared. Total phenol and caffeine were detected by spectroscopy. Quantification of heavy metals was done by digestion methods and examined by atomic absorption spectrophotometer.

The Mesn±SD amounts of total phenolic content, caffeine, lead, cadmium, and chromium in green tea from all regions comprised 27.13±1.54%, 3.20±0.01%, 0.81±0.66 ppm, 1.54±1.39 ppm, and 0.28±0.20 ppm, respectively, and these amounts in black tea were 14.90±1.53%, 3.20±0.05%, 1.00±0.79 ppm, 1.65±0.93 ppm, and 0.24±0.15 ppm, respectively.

The content of total phenol and lead in tea was different in various regions of Gilan Province. Green tea contains more phenolic compounds than black tea, but the caffeine in green and black tea is almost equal. The amounts of cadmium and chromium in some Gilan Province areas are higher than the standard level, which needs to be investigated.

In this study, the ferrous sulfate was used to remove Cr(VI) and Ni(II) ions from a real Ni-Cr plating industry wastewater. This is an applied study. The type of sampling was composite by three 5 L containers. Wastewater chemical and physical characteristics were measured in accordance with the standard methods book 14. The concentration of un-removed metal ions was estimated by ICP-OES. The Jar test type experiment was used to carry the chemical coagulation experiment. The results indicated that the rate of removal would depend on the pH estimation of 1.5-11, the diverse contact time in the range of 30-120 min and the coagulant measurement in the range of 0.5-2 g/l. The optimum Cr(VI) ions removal was gotten at a pH of 7 up to 83.88% in 0.5 g/l of coagulant dose in 40 min. While the optimum Ni(II) ions removal was found to occur at a pH of 5 up to 56.33 % in 0.5 g/l of coagulant measurements in 40 min. The scanning electron microscopy results reveal the difference between the coagulant surface when coagulation. Also, the energy-dispersive x-ray spectroscopy (EDX) analysis shows the presence of Cr(VI) and Ni(II) ions on the surface of the ferrous sulfate after coagulation. Ultimately, the outcomes indicated that ferrous sulfate could be an operative chemical coagulant to remove Cr(VI) and Ni(II) ions from the plating industry wastewater, especially for Cr(VI) particles. The outcome of this study can be a useful guide to the real plating industry wastewater treatment operators.

Due to the lack of information about the positive or negative effects of L-carnitine, chromium, vitamin D, and the uptake of a safe dietary supplement to reduce the effects of diabetes, it seems essential to determine the effects of these drugs on diabetes.

Wistar rats were divided into 12 groups, control, diabetic, and intact, each of which was treated with metformin, L-carnitine, vitamin D, and chromium or a combination of L-carnitine, vitamin D, and chromium. The serum levels of liver function parameters, iron, TIBC, Catalase and GPX activities were measured. Data were statistically analyzed by one-way ANOVA using SPSS 18 software. Statistical significance among the groups was determined using LSD test, and P-value< 0.05 was considered significant in all cases.

AST activity in diabetic groups and those receiving chromium and L-carnitine has significantly reduced (P-value= 0.009). A significant reduction in ALT and ALP activity in the diabetic groups receiving vitamin D and combined and non-diabetic groups receiving metformin were observed, in contrast to a significant increase in ALT activity in diabetic recipients of L-carnitine (P-value= 0.009).

L-carnitine, chromium, and vitamin D supplements have synergistic effects and a combination of them has the best protective effect on factors that have been studied.

According to Hindu mythology, Yamuna River plays an impotent role as a holy water resource in Delhi, India. The lead and chromium concentrations were determined from the water samples collected from five different locations around this river in Delhi area. The contaminated water from this river is mostly used for drinking, agriculture, aquaculture, and storage as a holy water.

The seasonal variations of heavy metal concentrations in the water samples collected from Yamuna river were determined for the summer, monsoon and winter supplies, using Inductively Coupled Plasma Mass Spectrometry (ICP-MS) and Atomic Absorption Spectroscopy (AAS).

In the summer water samples, we found greater concentrations of both heavy metals than those for the monsoon season. The concentrations of lead and chromium in the water samples were higher than the permissible limits recommended by the World Health Organization (WHO). The water quality was not safe for drinking, cleaning and agriculture, nor for the aquatic animals, such as fish, amphibians and others.

The condition of the water in Yamuna river is of great health concerns. Therefore, it is vital to take necessary actions to decontaminate the water from this river, and to draw effective strategies to minimize or prevent the current and future contaminations added to this important water resource in India.

The aim of this work is to exploit low cost and efficient sorbent for removal of heavy metals from the aqueous solution using Mallet Flower Leaf Powder (MFLP). MFLP is processed into a fine powder and used as a bio-adsorbent. Experiments are conducted to find out the feasibility of metal recovery process to reclaim the metals. The adsorption rates of both Chromium and Copper are lowered by 3.4% and 48.4% respectively in contrast to those obtained when only one metal is present in the solution. The presence of Copper along with Chromium has not much affected the adsorption rates of Chromium. There is higher adsorption rate for Chromium than for Copper at different temperatures. In the binary system, the copper adsorption rate is found to be suppressed by the presence of Cr(VI). The uptake of Cr(VI) is higher in the binary system than the single system, while the uptake of Cu(II) is lower in the binary system than the single system. The effect of initial concentration on recovery of Cu(II) from loaded adsorbent decreases up to 60 mg/l where about 68% recovery was found. The maximum recovery for Cu(II) was found to be at an adsorbent dosage in the range 15-35 g. As the initial concentration of Cu(II) increases, the retention of metal on MFLP increases. The data collected are verified with the kinetic studies. The results suggested favorable removal efficiency of copper and chromium from waste water using MFLP.

Heavy metals and its compounds are toxic pollutants that have priority in the studies due to their potential harm to human health.

This study evaluated the potential of a chicken feather for the removal of nickel and chromium from aqueous solutions. The chicken feather was prepared from aviculture for nickel and chromium removal from aqueous solutions. The effects of pH, contact time, adsorbent dosage, and initial metal concentration on Ni and Cr removal were also evaluated in this study. Freundlich and Langmuir isotherm models were used to characterize the biosorption of the mentioned metals onto the chicken feather.

Based on the findings, the maximum removal of metals was found in a contact time of 3 h, 1 g/L of adsorbent, pH 5 (for Ni) and 6 (for Cr), and concentration of 1 mg/l of metals. According to the Langmuir isotherms, the maximum biosorption capacities (qm) of Cr and Ni were 22.3 and 119.05 mg/g, respectively.

The results showed that chicken feathers can absorb chromium and nickel at low concentrations. However, the ability and possibility of the use of the chicken feather are limited for the treatment of contaminated wastewater at high concentrations.

Field matching problems in abutting electron fields can be managed by using spoilers.

The aim of this study was to design a Monte Carlo framework for the assessment of spoiler application in abutting electron fields.

In this experimental study, a Siemens Primus treatment head was simulated for a 5 MeV electron beam using BEAMnrc, DOSXYZnrc and EGSnrc user codes. Validation of beam model was done by measurement using a MP3-M water tank and a Semi-flex Chamber-31010 (PTW, Freiburg, Germany). An in-house routine was developed to calculate the combined isodose curves resulting from simulated adjacent fields. The developed framework was analyzed using PMMA and chromium spoilers.

The penumbra width increased from 27.5 mm for open fields to 42 mm for PMMA and 40 mm for chromium. The maximum junction dose reduced from 115% for open fields to 107% for PMMA and 108% for chromium. R90 reduced about 6 mm for PMMA and 3 mm for chromium. Uniformity index reduced from 93% to 77% for both spoilers. Surface dose increased from 79% to 89% for PMMA and 88% for chromium.

Using spoilers, penumbra width at the surface was increased, size and depth of hot spots as well as the therapeutic range were reduced and dose homogeneity at the junction of abutting electron fields was improved. For both spoilers, the uniformity index reduced, and surface percent dose increased. The results of this research can be used to optimize dose distribution in electron beam treatment using abutting fields.

Brucellosis is a common infectious disease around the globe. The aim of the present investigation was to evaluate the effect of brucellosis on the serum levels of chromium (Cr), lead (Pb), soluble tumor necrosis factor-like weak inducer of apoptosis (sTWEAK) as well as high-sensitivity C-reactive protein (hsCRP) and homocysteine in patients suffering from brucellosis. The present case-control study was executed on 40 treated brucellosis patients (case) and 40 healthy individuals (control). Blood samples were obtained from all the participants for the measurement of the desired indices. The serum levels of chromium in the case group (0.109±0.025 μg/L) was significantly lower compared with that in the control group (0.121±0.027 μg/L, P=0.047). The levels of lead in serum were almost unchanged between the two groups (12.58±1.94 vs. 12.28±2.42 μg/dL, P=0.533). The sTWEAK levels were significantly lower in the case group as compared to the control subjects (235.20±48.45 pg/mL vs. 262.00±67.25 pg/mL, P=0.044). The levels of hs-CRP were significantly higher in the case group (2.23±0.34 mg/L) than that in the control group (2.05±0.32 mg/L, P=0.016); similarly, homocysteine levels were higher in the serum of patients in case group as compared to the control ones (16.18±4.47 µmol/L vs. 14.36±3.06 µmol/L, P=0.038). The current investigation underlined that brucellosis causes alterations in serum chromium and sTWEAK levels, the markers that are considered as the predictors of cardiovascular disease.

Type 1 diabetes mellitus is believed to be caused by decline of insulin secretion because of destruction of the pancreatic β cell, which is characterized with symptoms such as hyperglycemia, polyuria, polydipsia, weight loss, and other symptoms. Due to the lack of sufficient data about protective effect of L-carnitine, chromium, and vitamin D as compared with metformin on biochemical indices in streptozotocin-diabetic rats, it seems necessary to determine the effects of these medications on diabetes.

Sixty Wistar rats were divided into 12 diabetic and healthy groups, and 10 groups of witness, metformin )150 mg/kg(, L-carnitine )200 mg/kg(, and chromium )2 mg/kg(, vitamin D (0.06 µg) and a group treated with simultaneous combined therapy of L-carnitine, chromium, and vitamin D. Diabetes mellitus was induced by streptozotocin. Rats with glucose levels of more than 300 mg/dL were considered as diabetic. After 30 days of treatment, the serum concentrations of renal parameters, lipid profile, malondialdehyde, and activity of superoxide dismutase were measured in the studied groups.

Malondialdehyde had a significant decrease in all diabetic groups but an increase in nondiabetic metformin and L-carnitine groups (P < 0.05). In all groups, a significant reduction of triglyceride was observed (P < 0.05). Urea increased in the diabetic metformin and chromium treatment groups, whereas in the other groups it decreased (P < 0.05). Among diabetic metformin groups, a significant increase in serum creatinine was found (P < 0.05). High-density lipoprotein also decreased in the combined group of L-carnitine, chromium, and vitamin D (P < 0.05). Cholesterol in diabetic L-carnitine, chromium treatment, and combined group showed a significant decrease (P < 0.05).

These data showed that all three drugs of L-carnitine, chromium, and vitamin D such as metformin seemed appropriate, which had the hypoglycemic, antilipidemic, and antioxidant effects.