Factors that Affect the Outcomes in Children with Decompensated Shock

Shock is an important causes of mortality and morbidity among children. Hypovolemic shock is the most common one and needs early recognition and rapid intervention patients. The aim of this study is to determine the effective factors on the outcome of children with decompensate shock. In this retrospective study in a pediatric Intensive Care Unit (PICU) outcome was determined in two groups, those who discharged and those who deceased Characteristics patients’ in each groups including: age, sex, etiology of the shock, laboratory findings, organ involvement and early or late interventions compared between two groups. predictors of mortality were thrombocytopenia, presence of respiratory failure and renal failure, hematologic and neurologic dysfunction, early use of volume expander, early intubation and early use of sedation. Parameters such as age, sex, leukocytes count and cardiovascular and liver dysfunction were not significantly different between two groups. In multivariate study, early intubation (OR=1.17, 95%CI=1.07-1.28, p=0.05) and early use of sedation (OR=1.36, 95%CI=1.09-1.42, p=0.04) were the only dependent predictor of mortality. Early intubation and sedation are reliable predictors of mortality in pediatric patients with decompensated shock.