Comparison of analgesia and side effects fentan yl or sufentanil with bupivacaine in lower limb orthopedic surgery patients using continuous infusion epidural

Postoperative pain is one of the most common problems after surgery،especially orthopedic surgery which if not prevent the onset or inadequate treatment، especially in older irreparable adverse reactions to be followed. Analgesic use of continuous epidural infusion in lower limb surgery with simultaneous use of local anesthetic drugs and narcotics is one of the most effective and safest methods of analgesic than the other methods is systemic. This study as double blind clinical trial was conducted، 82 patients undergoing lower limb orthopedic surgery in two groups randomly divided into 41 equal and after insertion of the epidural catheter before surgery، after surgery in all stages Patients pump analgesia epidural continuous infusion with two diet drug F (bupivacaine 0. 125 % + fentanyl 5 micr/ ml) and S (bupivacaine 0. 125 % + sufentanil 0. 5 micr/ ml) with a speed of 5ml/ h Connected. The pain intensity based on (VAS) and side of motor block، nausea and vomiting، itching، urinary retention،hypotension and respiratory depression during 1، 3، 8، 16، 24، 48 hours after surgery in both groups measured and recorded. The demographic in both groups، similar to one another. The mean pain scores (VAS) during activity than resting there، but the total in both S and F mean pain scores during activity and rest less than 3 was And a significant difference does not show the different hours. Hypotension in the first hour in group F than the S group had significantly increased، but at other hours is not a significant difference. Motor block and nausea and vomiting، although in Group S than Group F، but the difference was not significant. Difference in other complications (pruritus، sedation،respiratory depression) between the two groups is not significant. This study shows that both fentanyl and sufentanil regimen with bupivacaine in epidural analgesia with continuous infusion led to similar analgesia and acceptable side effects except the first hour of hypotension after surgery.