The relationship between serum level of 25- hydroxy vitamin D with anthropometric indices and some biochemical parameters in obese women

Some studies have shown that the serum concentration of 25- hydroxy vitamin D which is represent the status of body vitamin D، has a diverse relationship with obesity status، and the risk of obesity decreases in people with high level of 25- hydroxy vitamin D. The aim of this study is to investigate the correlation between the serum level of 25- hydroxy vitamin D and anthropometric indices، glucose، lipid profile، serum insulin، and insulin resistance in obese women.

This study was carried out on 43 obese women and 43 healthy women with normal weight as a control group، aged 20-50. They were matched for age and physical activity. For each participant، a 3-day 24-hours food recall was filled. Moreover، fasting blood sampling was taken to measure blood levels of fasting blood glucose، 25- hydroxy vitamin D، lipid profile and serum insulin.

The mean level of serum 25- hydroxy vitamin D، insulin and also insulin resistance based on IR-HOMA index in the group of obesity and control were 28. 05 ± 16. 66 versus 25. 72 ± 14. 08 (P=0. 48)، 25. 97 ± 7. 53 versus 25. 93 ± 9. 32 (P=0. 98)، and 6. 39 ± 2. 6 versus 5. 83 ± 2. 5 (P=0. 30) respectively. Between the anthropometric indices، 25- hydroxy vitamin D had a significant relationship only with body weight in obese group (p=0. 033، r= 0. 326). No significant relationship was observed between serum 25- hydroxy vitamin D with blood sugar، lipid profile، serum insulin level and HOMA-IR in obese women.

No significant relationship was seen between serum level of 25- hydroxy vitamin D with anthropometric indices (except for body weight)، serum levels of glucose، lipid profile and insulin resistance in the obese women.