Study of Group A -Hemolytic Streptococci Colonization and Resistance Drug of Isolates on 12-14 Year Old Healthy Students of Aras Free Zone Schools

Group A -Hemolytic Streptococci are the most prevalent pathogenic bacteria that can cause rheumatic fever and acute glomerulonephritis in adolescents so its correct diagnosis and treatment is very important. This study was done with multi stage random sampling method between three hundred 12-14 year old healthy students in Aras Free Zone guidance schools. Sixty seven group A -Hemolytic Streptococcus (GABHS) strains were isolated and were tested with disc diffusion method against sixteen antibiotics including Penicillin, Erythromycin and some second line drugs such as Amoxicillin, Ampicillin, Coamoxiclav, Tobramycin, Gentamicin, Clindamycin, Vancomycin, Tetracycline, Cotrimoxazole, Cloxacillin, Cephalothin, Cephalaxin, Cefazolin, Cefixime. This study indicated that of 300 students, %22 were healthy carriers of GABHS. Of 67 healthy carriers, 17 cases (%27) were female students of first base class that was the highest rate, whereas 4 cases (%8.5) were female students of second base class that was the lowest rate. All of GABHS strains (%100) were sensitive to Penicillin and resistance to Cotrimoxazole and Clavulanic acid were detected up to %92 and %89 respectively. Our results showed that prescription of second line drugs must be prescripted more cautiously.