A Case Report of Nodular Regenerative Hyperplasia

Nodular regenerative hyperplasia is a rare cause of portal hypertension. Clinical findings are consist of complication of portal hypertension such as variceal bleeding. Histopathology is key of diagnosis. Case report: Patient was a 44 years old woman with a chief complaint of flank pain and easy bruising. She had a history of hematemesis many years ago. In physical examination، she had huge splenomegaly and ecchymoses on lower extrimities. Lab data are normal except for pancytopenia. In upper endoscopy، esophageal varices and portal hypertensive gastropathy were seen. Subsequently، she was found to have nodular regenerative hyperplasia on liver biopsy. Esophageal varices banded successfully and she was asymptomatic on Beta blocker after wards. Nodular regenerative hyperplasia should be considered in the differential diagnosis of any patient with portal hypertension without cirrhosis.