The effect of Evening Primrose and Vitex on cyclic Mastalgia in comparison with vitamin E: a randomized clinical trial

Mastalgia is a one of the most common reasons for consultation to all the women who make repeated visits to health care centers. The aim of this research was to compare the effect of Evning primrose and Vitex on mastalgia. This study is a one-stage clinical trials which carried out on 210 women with Mastalgia whom were placed in three groups of 70. The first group: Vitex tablets، the second group: primrose capsules and the control group: vitamin E were given for 2 months. Before and 2 months after the intervention scores for chest pain were campared and evaluated by a questionnaire. The results were analyzed using SPSS software. Results showed that the mean pain score in the intervention group has dropped and average days without pain have increased in the three groups and average days with moderate pain decreased in all three groups and average days with severe pain have decreased in all three groups (Cardiff chart) (p<0. 0001). Statistical tests showed that the effect of Vitex has been more than the others (p<0. 0001). The results showed that Vitex، has a good therapeutic effect on cyclic Mastalgia and can be used as an effective treatment.