Prevalence and pattern of congenital malformations in newborn in Rafsanjan, Iran (2007-08)

Congenital malformations are among important causes of morbidity and mortality in newborns. This study was done to determine the prevalence and pattern of congenital malformations in newborn. This descriptive study was done on 6089 newborns in maternity center in Rafsanjan، Iran during 2007-08. The newborns were examined by pediatricians and based on clinical examination; the type of obvious of either minor or major malformations were recorded. The 179 cases had at least a major or minor malformations. Over all the prevalence of malformations was 2. 93%. The highest prevalence of obvious malformations was seen in the musculo-skeletal (43. 5%)، followed by genitourinary (22. 9%) and cardiovascular systems (15. 08%). There was significant relation between congenital malformations، gestational age and medicine used by mothers (P<0. 05). The highest prevalence of obvious malformations was seen in the musculo-skeletal system.