Effect of Depo-Provera on depression

Depression is one of the common psychiatric disorders which are more common in women in the reproductive ages. So this study is to investigate the effect of Depo-Provera on depression. This cross-sectional study was performed on 70 women who had chosen Depo-Provera as contraception. Beck test was done at arrival and repeated 3 months later، and the scores obtained were compared by paired t test. The participants BDI scores at baseline were equal to 7. 89±3. 85 while 3 months after treatment with the scores were equal to 7. 09±3. 63 which were significantly decreased. Since Depo-Provera reduces depressive symptoms in women who take it and does not increase these symptoms in women with a history of depression، it seems that Depo-Provera is an appropriate choice as contraception.