The Effect of A Short Time Exercise on Adiponectin And Insulin Sensitivity in Type 2 Diabetic Patients: A Short Report

The accumulating evidence indicates that systemic inflammation is related with obesity and type II diabetes. In the present study، serum adiponectin and insulin sensitivity responses to a short-time exercise test were investigated in type II diabetic patients. In this semi-experimental study، fasting level of serum adiponectin، glucose، insulin sensitivity، total cholesterol (TC)، triglyceride (TG) and high density lipoprotein (HDL) were compared in adult males with type 2 diabetic (n= 15، 42. 50±5. 34 year) and none-diabetic (n= 15، 41. 33±4. 26 year) patients. In addition، the responses of these variables to a short-time exercise test were measured in diabetic patients. In diabetic patients، serum adiponectin (5. 33±0. 48 versus 10. 58±0. 83) and insulin sensitivity (0. 48±0. 01 versus 0. 66±0. 02) was lower and glucose (242. 33±19 versus 97. 28±5)، insulin (8. 52±0. 53 versus 6. 14±0. 48) and cholesterol (203. 16±11 versus 135. 65±19) was higher than non-diabetic subjects (p<0. 05). Exercise test led to significant increase in serum adiponectin (5. 33±0. 48 versus 7. 33±0. 67) and significant decrease in glucose (242. 33±19 versus 217. 46±21)، TG/HDL (3. 90±0. 57 versus 3. 57±0. 56)، TC/HDL (4. 29±0. 11 versus 4. 01±0. 12) without changes in insulin sensitivity in diabetic patients. Type 2 diabetic patients have lower adiponectin and insulin sensitivity than non-diabetic subjects. A short- term exercise test increases serum adiponectin in the absence of change in the insulin sensitivity in diabetic patients.